The study of synergistic laws and patterns made it possible to substantiate and explain the possibility of their transfer to the plane of the theory of management of economic security of the enterprise in order to develop tools for synergistic management of economic security of the enterprise. The definition of the concept of “economic security of the enterprise” is proposed, which represents the ability to resist it as an ectropic factor to the influence of threats to the environment, ie the supersystems (countries and industries) as an entropy factor, as well as ability to respond to threats in a coordinated way. An algorithm for substantiating the choice of strategies for managing the economic security of the enterprise has been developed; using this algorithm based on the detection of bifurcation points and their analysis, it is possible to identify the type of crisis and take into account the existence of the internal mechanism of development inherent in the economic security of the enterprise in a certain period - adaptation or bifurcation, according to which it is necessary to develop The paper emphasizes that a high level of economic security of the enterprise depends on the formation of synergistic effects, as well as on the ability to establish coherent or coordinated relationships that will lead to cooperative processes. Three types of synergetic effects resulting from management actions are considered: functional (this is a result equivalent to the sum of the component parts), positive (this is a result that exceeds the sum of the component parts) and negative (this is a result that is less than the sum of the component parts).