The article examins the concept of the defense-industrial complex as the basis of the national security of the state, peculiarities of its structure and functioning in different countries of the world, as well as issues related the current state and reforms in Ukraine. In particular, the essence of the concept of defense-industrial complex is determined by researching the scientific points of view of both foreign and Ukrainian scientists. Peculiarities of the structure and functioning of the defense-industrial complex in countries like the USA, France, Italy, Great Britain, Sweden, China, India and Germany were studied. It was shown which state organs in Ukraine are responsible for production and supply (sales) of weapons and military equipment. The legal status of the State Concern “Ukroboronprom” as an important component of the defense-industrial complex of Ukraine has been determined. Special attention is paid to the peculiarities of the strategy of development of the defense-industrial complex of Ukraine for the period till 2028, its main purpose and priority directions are highlighted. Key strategic goals and key strategic initiatives in the State Concern “Ukroboronprom” reform strategy are highlighted, with the aim of achieving close international cooperation in the framework of innovative tendencies and improvement of the legal framework by bringing the legislation norms to the world standards. Problematic issues in the defense industry of Ukraine that need to be addressed in order to improve the efficiency and consistency of this sector of economy were identified.