Important role in the implementation of a proactive approach represents operations dedicated to elimination of weapons of mass destruction. It is obvious that if trained and adequately equipped military forces carried out an operation to eliminate weapons of mass destruction, it significantly reduces the need to organize extensive CBRN defence measures for military forces or protection of civilians. Measures to implement the tasks of defence against weapons of mass destruction (CBRN defence) recently change. The security environment influences the perception and attitude of the Alliance to address global problems associated with state or non-state ownership of weapons of mass destruction. The focus of the Chemical Corps is gradually expanding from the current passive (reactive) approach to proactive approach.